Hello,
I was using the Palimpsest package to calculate the contribution of each SBS to the total sample mutations in my data.
the deconvolution_fit fuction uses the provided SBS_cosmic (ref) as input_signatures as in the illustrated example.
can you provide a DOI / pubmed id for that reference.
In The hep page I find that the reference was taken from Alexandrov et al. (2018)
is it this one https://doi.org/10.1038/nature25795 ?
Hello,
I was using the Palimpsest package to calculate the contribution of each SBS to the total sample mutations in my data.
the deconvolution_fit fuction uses the provided SBS_cosmic (ref) as input_signatures as in the illustrated example.
can you provide a DOI / pubmed id for that reference.
In The hep page I find that the reference was taken from Alexandrov et al. (2018)
is it this one https://doi.org/10.1038/nature25795 ?
(https://cog.sanger.ac.uk/cosmic-signatures-production/documents/COSMIC_v3.1_SBS_GRCh37.txt)
dim(Palimpsest::SBS_cosmic)
[1] 65 96
dim(read.table("COSMIC_v3_SBS_GRCh37.txt",header=TRUE))
[1] 96 68
The SBS84 SBS85 were not implemented in the SBS_cosmic.rda file