Hi, Just a note but the current implementation prevents anyone from discarding alignments with very low AS scores as `-T 0` is a fixed append. https://github.com/ICGC-TCGA-PanCancer/Seqware-BWA-Workflow/blob/64d5e6c64cc1f2dee26f5459ecd73d4865448a78/src/main/java/com/github/seqware/WorkflowClient.java#L318