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fix error in spreadsheet, update DOI, JSON
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README.md

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# Indication Mechanism of Action Database
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A database of paths that represent the mechanism of action from a drug to a disease in an indication.
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> [**Database of mechanism of action paths for selected drug-disease indications**](https://zenodo.org/record/3515487)
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> [**Database of mechanism of action paths for selected drug-disease indications**](https://zenodo.org/record/3516335)
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<br><Small>Mayers, Michael; Steinecke, Dylan; Su, Andrew I.<small><br>
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[![DOI](https://zenodo.org/badge/DOI/10.5281/zenodo.3515518.svg)](https://doi.org/10.5281/zenodo.3515518)
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[![DOI](https://zenodo.org/badge/DOI/10.5281/zenodo.3516335.svg)](https://doi.org/10.5281/zenodo.3516335)
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## Purpose
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## Curation
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Indications were selected at random from the set contained within DrugCentral. Half were taken from the full set,
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Indications were selected at random from the set contained within DrugCentral. Half were taken from the full set,
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representing a set of common drug disease pairs, and the other half were selected from a pool of less-common diseases
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to vary the targets and diseases treated.
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to vary the targets and diseases treated.
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Paths were derived from free-text descriptions found on DrugBank, Wikipeida and within literature. Concepts within the
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Paths were derived from free-text descriptions found on DrugBank, Wikipeida and within literature. Concepts within the
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text were then normalized to a concept type (Drug, Protein, Pathway, etc) and relationships between the concepts were
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determined from the source. Finally concepts were mapped to an identifier depending on the concept type according to
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determined from the source. Finally concepts were mapped to an identifier depending on the concept type according to
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the following table:
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|Concept Type | Identifier Source|
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|Drug | MESH, DrugBank |
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|Molecular Function | GO |
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|Pathway | REACT |
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|Phenotype | HP |
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|Phenotype | HP |
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|Protein | UniProt |
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|Protein Family | InterPro |
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|Taxon | NCBITaxon |

indication_paths.json

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"id": "MESH:D010146",
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"name": "Pain",
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"label": "Disease"
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},
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{
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"id": null,
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"name": "Pain",
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"label": null
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}
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],
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"links": [
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"source": "GO:0019233 ",
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"target": "MESH:D010146",
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"key": "CAUSES"
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},
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{
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"source": "MESH:D010146",
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"target": null,
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"key": null
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}
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]
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},
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}
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]
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}
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]
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]

xls_to_json.py

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from biothings_client import get_client
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mg = get_client('gene')
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file_location = "https://zenodo.org/record/3515518/files/indication_MOA_paths.xlsx?download=1"
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file_location = "https://zenodo.org/record/3516335/files/indication_MOA_paths.xlsx?download=1"
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all_sheets = pd.read_excel(file_location, None)
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# Dereference each sheet into an individual variable

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