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# GENERATED AUTOMATICALLY, DO NOT EDIT
- id: 10.1038/s44320-026-00197-7
title: Progress and new challenges in image-based profiling
authors:
- Erik Serrano
- John Peters
- Jesko Wagner
- Rebecca E Graham
- Zhenghao Chen
- Brian Y Feng
- Gisele Miranda
- Alexandr A Kalinin
- Loan Vulliard
- Jenna Tomkinson
- Cameron Mattson
- Michael J Lippincott
- Ziqi Kang
- Divya Sitani
- Dave Bunten
- Srijit Seal
- Neil O Carragher
- Anne E Carpenter
- Shantanu Singh
- Paula A Marin Zapata
- Juan C Caicedo
- Gregory P Way
publisher: Molecular Systems Biology
date: '2026-03-27'
link: https://doi.org/hbxfz5
tags:
- image-based profiling
- review
image: https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs44320-026-00197-7/MediaObjects/44320_2026_197_Fig1_HTML.png?as=webp
- id: 10.64898/2026.04.15.718737
title: Single-cell hit calling in high-content imaging screens with Buscar
authors:
- Erik Serrano
- Wei-shan Li
- Gregory Way
publisher: openRxiv
date: '2026-04-19'
link: https://doi.org/hb35zs
tags:
- software
- hit calling
- high-content screening
- single-cell
image: https://raw.githubusercontent.com/WayScience/buscar/main/logo/just-icon.png
extra-links:
- type: source
link: https://github.com/WayScience/Buscar
text: GitHub
- id: 10.1101/2025.11.14.688518
title: Characterizing the landscape of gene process dependencies in cancer
authors:
- Julia B. Curd
- Gregory P. Way
publisher: openRxiv
date: '2025-11-16'
link: https://doi.org/hb35zt
tags:
- cancer
- gene dependencies
- CRISPR
extra-links:
- type: source
link: https://github.com/WayScience/gene_dependency_representations
text: Analysis code
- id: 10.1101/2025.10.23.684203
title: High-content live-cell time-lapse imaging predicts cells about to die via
apoptosis
authors:
- Michael J. Lippincott
- Jenna Tomkinson
- Ibrahim Bilem
- Mahomi Suzuki
- Akiko Nakde
- Toshiaki Endou
- Simon Mathien
- Felix Lavoie-Perusse
- "Carla Basualto-Alarc\xF3n"
- Gregory P. Way
publisher: openRxiv
date: '2025-10-24'
link: https://doi.org/hb35zv
tags:
- live-cell imaging
- apoptosis
- cell death
- time-lapse
- id: 10.1101/2025.10.14.682427
title: Stellar quality control for single-cell image-based profiling with coSMicQC
authors:
- Jenna Tomkinson
- Dave Bunten
- Gregory P. Way
publisher: openRxiv
date: '2025-10-15'
link: https://doi.org/hb35zw
tags:
- software
- quality control
- single-cell
- image-based profiling
extra-links:
- type: source
link: https://github.com/WayScience/coSMicQC
text: GitHub
image: https://raw.githubusercontent.com/cytomining/cosmicqc/main/media/logo/just-icon.png
- id: 10.1016/j.patter.2026.101514
title: Scalable data harmonization for single-cell image-based profiling with CytoTable
authors:
- Dave Bunten
- Jenna Tomkinson
- Erik Serrano
- Michael J. Lippincott
- Kenneth I. Brewer
- Vince Rubinetti
- Faisal Alquaddoomi
- Gregory P. Way
publisher: Patterns
date: '2026-05-01'
link: https://doi.org/hbvg3p
image: https://raw.githubusercontent.com/cytomining/cytotable/master/logo/just-icon.png
tags:
- software
- image-based profiling
- single-cell
- data harmonization
extra-links:
- type: source
link: https://github.com/cytomining/CytoTable
text: GitHub
- id: 10.1038/s41467-025-61547-x
title: Combining phenomics with transcriptomics reveals cell-type-specific morphological
and molecular signatures of the 22q11.2 deletion
authors:
- Matthew Tegtmeyer
- Dhara Liyanage
- Yu Han
- Kathryn B. Hebert
- Ruifan Pei
- Gregory P. Way
- Pearl V. Ryder
- Derek Hawes
- Callum Tromans-Coia
- Beth A. Cimini
- Anne E. Carpenter
- Shantanu Singh
- Ralda Nehme
publisher: Nature Communications
date: '2025-07-09'
link: https://doi.org/hb35zx
tags:
- cell morphology
- transcriptomics
- 22q11.2
- phenotyping
- id: 10.1161/CIRCULATIONAHA.124.071956
title: Cell Painting and Machine Learning Distinguish Fibroblasts From Nonfailing
and Failing Human Hearts
authors:
- Joshua G. Travers
- Jenna Tomkinson
- Marcello Rubino
- Marion Delaunay
- Michael R. Bristow
- Gregory P. Way
- Timothy A. McKinsey
publisher: Circulation
date: '2025-04-22'
link: https://doi.org/g9wt6s
image: https://www.ahajournals.org/cms/10.1161/CIRCULATIONAHA.124.071956/asset/eb5df843-0afb-4f37-bf75-265f17c7ec93/assets/graphic/circulationaha.124.071956.fig01.jpg
tags:
- high-content microscopy
- cell painting
- cardiac fibrosis
extra-links:
- type: source
link: https://github.com/WayScience/cellpainting_predicts_cardiac_fibrosis
text: Analysis code
- id: 10.1091/mbc.E25-03-0119
title: A morphology and secretome map of pyroptosis
authors:
- Michael J. Lippincott
- Jenna Tomkinson
- Dave Bunten
- Milad Mohammadi
- Johanna Kastl
- Johannes Knop
- Ralf Schwandner
- Jiamin Huang
- Grant Ongo
- Nathaniel Robichaud
- Milad Dagher
- "Andr\xE9s Mansilla-Soto"
- Cynthia Saravia-Estrada
- Masafumi Tsuboi
- "Carla Basualto-Alarc\xF3n"
- Gregory P. Way
publisher: Molecular Biology of the Cell
date: '2025-06-01'
link: https://doi.org/g9wt6t
image: https://www.molbiolcell.org/cms/10.1091/mbc.E25-03-0119/asset/images/large/mbc-36-ar63-g001.jpeg
tags:
- cell death
- high-content microscopy
- multimodal data
extra-links:
- type: source
link: https://github.com/WayScience/pyroptosis_signature_image_profiling
text: Data processing
- type: source
link: https://github.com/WayScience/pyroptosis_signature_data_analysis
text: Analysis code
- id: 10.1038/s41467-025-60306-2
title: A versatile information retrieval framework for evaluating profile strength
and similarity
authors:
- Alexandr A. Kalinin
- John Arevalo
- Erik Serrano
- Loan Vulliard
- Hillary Tsang
- Michael Bornholdt
- "Al\xE1n F. Mu\xF1oz"
- Suganya Sivagurunathan
- Bartek Rajwa
- Anne E. Carpenter
- Gregory P. Way
- Shantanu Singh
publisher: Nature Communications
date: '2025-06-04'
link: https://doi.org/g9wt6v
image: https://www.biorxiv.org/content/biorxiv/early/2024/04/02/2024.04.01.587631/F1.large.jpg
tags:
- drug screening metric
- software
- profiling
extra-links:
- type: source
link: https://github.com/cytomining/copairs
text: Software
- id: 10.1038/s41592-025-02611-8
title: Reproducible image-based profiling with Pycytominer
authors:
- Erik Serrano
- Srinivas Niranj Chandrasekaran
- Dave Bunten
- Kenneth I. Brewer
- Jenna Tomkinson
- Roshan Kern
- Michael Bornholdt
- Stephen J. Fleming
- Ruifan Pei
- John Arevalo
- Hillary Tsang
- Vincent Rubinetti
- Callum Tromans-Coia
- Tim Becker
- Erin Weisbart
- Charlotte Bunne
- Alexandr A. Kalinin
- Rebecca Senft
- Stephen J. Taylor
- Nasim Jamali
- Adeniyi Adeboye
- Hamdah Shafqat Abbasi
- Allen Goodman
- Juan C. Caicedo
- Anne E. Carpenter
- Beth A. Cimini
- Shantanu Singh
- Gregory P. Way
publisher: Nature Methods
date: '2025-03-03'
link: https://doi.org/g863nc
image: https://raw.githubusercontent.com/cytomining/pycytominer/master/logo/just-icon.png
tags:
- image-based profiling
- bioinformatics
- software
- cell morphology
extra-links:
- type: source
link: https://github.com/cytomining/pycytominer
text: GitHub
- id: 10.1101/2024.09.11.612546
title: High-content microscopy and machine learning characterize a cell morphology
signature of<i>NF1</i>genotype in Schwann cells
authors:
- Jenna Tomkinson
- Cameron Mattson
- Michelle Mattson-Hoss
- Herb Sarnoff
- Stephanie J. Bouley
- James A. Walker
- Gregory P. Way
publisher: Cold Spring Harbor Laboratory
date: '2024-09-16'
link: https://doi.org/g863nd
image: https://www.biorxiv.org/content/biorxiv/early/2024/09/16/2024.09.11.612546/F1.large.jpg
tags:
- image-based profiling
- neurofibromatosis type 1
- cell morphology
- assay development
extra-links:
- type: source
link: https://github.com/WayScience/nf1_schwann_cell_morphology_signature
text: Analysis code
- type: source
link: https://github.com/WayScience/nf1_schwann_cell_painting_data
text: Data processing code
- id: 10.1038/s41592-024-02537-7
title: A genome-wide atlas of human cell morphology
authors:
- Meraj Ramezani
- Erin Weisbart
- Julia Bauman
- Avtar Singh
- John Yong
- Maria Lozada
- Gregory P. Way
- Sanam L. Kavari
- Celeste Diaz
- Eddy Leardini
- Gunjan Jetley
- Jenlu Pagnotta
- Marzieh Haghighi
- Thiago M. Batista
- "Joaqu\xEDn P\xE9rez-Schindler"
- Melina Claussnitzer
- Shantanu Singh
- Beth A. Cimini
- Paul C. Blainey
- Anne E. Carpenter
- Calvin H. Jan
- James T. Neal
publisher: Nature Methods
date: '2025-01-27'
link: https://doi.org/g826g9
image: https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41592-024-02537-7/MediaObjects/41592_2024_2537_Fig1_HTML.png
tags:
- image-based profiling
- pooled cell painting
- cell morphology
extra-links:
- type: source
link: https://github.com/broadinstitute/pooled-cell-painting-image-processing
text: GitHub
- id: 10.1101/2024.11.16.623947
title: Combining NeuroPainting with transcriptomics reveals cell-type-specific morphological
and molecular signatures of the 22q11.2 deletion
authors:
- Matthew Tegtmeyer
- Dhara Liyanage
- Yu Han
- Kathryn B. Hebert
- Ruifan Pei
- Gregory P. Way
- Pearl V. Ryder
- Derek Hawes
- Callum Tromans-Coia
- Beth A. Cimini
- Anne E. Carpenter
- Shantanu Singh
- Ralda Nehme
publisher: Cold Spring Harbor Laboratory
date: '2024-11-17'
link: https://doi.org/g863nf
image: https://www.biorxiv.org/content/biorxiv/early/2024/11/17/2024.11.16.623947/F1.large.jpg
tags:
- image-based profiling
- cell painting
- data integration
- id: 10.1186/s44330-024-00014-3
title: Toward generalizable phenotype prediction from single-cell morphology representations
authors:
- Jenna Tomkinson
- Roshan Kern
- Cameron Mattson
- Gregory P. Way
publisher: BMC Methods
date: '2024-12-09'
link: https://doi.org/g863ng
image: https://github.com/WayScience/phenotypic_profiling/blob/main/7.figures/figures/figure1_panelB.png?raw=true
tags:
- single-cell
- microscopy
- phenotype
extra-links:
- type: source
link: https://github.com/WayScience/phenotypic_profiling/
text: Analysis
- type: data
link: https://github.com/WayScience/mitocheck_data
text: Data
- type: source
link: https://github.com/WayScience/IDR_Stream
text: IDR_stream Software
- id: 10.1038/s41467-023-44045-w
title: High-dimensional phenotyping to define the genetic basis of cellular morphology
authors:
- Matthew Tegtmeyer
- Jatin Arora
- Samira Asgari
- Beth A. Cimini
- Ajay Nadig
- Emily Peirent
- Dhara Liyanage
- Gregory P. Way
- Erin Weisbart
- Aparna Nathan
- Tiffany Amariuta
- Kevin Eggan
- Marzieh Haghighi
- Steven A. McCarroll
- "Luke O\u2019Connor"
- Anne E. Carpenter
- Shantanu Singh
- Ralda Nehme
- Soumya Raychaudhuri
publisher: Nature Communications
date: '2024-01-06'
link: https://doi.org/gtct77
image: https://www.biorxiv.org/content/biorxiv/early/2023/01/09/2023.01.09.522731/F1.large.jpg
tags:
- cell painting
- data integration
- cell morphology
- id: 10.7554/eLife.91362
title: High-content microscopy reveals a morphological signature of bortezomib resistance
authors:
- Megan E Kelley
- Adi Y Berman
- David R Stirling
- Beth A Cimini
- Yu Han
- Shantanu Singh
- Anne E Carpenter
- Tarun M Kapoor
- Gregory P Way
publisher: eLife
date: '2023-09-27'
link: https://doi.org/gtcgdd
image: https://raw.githubusercontent.com/broadinstitute/profiling-resistance-mechanisms/master/3.resistance-signature/figures/bortezomib_roc_curve.png
repo: https://github.com/broadinstitute/profiling-resistance-mechanisms
tags:
- cancer resistance
- cell painting
- open science
- id: 10.1016/j.slasd.2023.08.009
title: Evolution and impact of high content imaging
authors:
- Gregory P. Way
- Heba Sailem
- Steven Shave
- Richard Kasprowicz
- Neil O. Carragher
publisher: SLAS Discovery
date: '2023-10-01'
link: https://doi.org/gtcgfv
image: https://ars.els-cdn.com/content/image/1-s2.0-S2472555223000667-gr2.jpg
tags:
- review
- high-content imaging
- id: 10.1101/2023.08.06.552164
title: A genome-wide atlas of human cell morphology
authors:
- Meraj Ramezani
- Julia Bauman
- Avtar Singh
- Erin Weisbart
- John Yong
- Maria Lozada
- Gregory P. Way
- Sanam L. Kavari
- Celeste Diaz
- Marzieh Haghighi
- Thiago M. Batista
- "Joaqu\xEDn P\xE9rez-Schindler"
- Melina Claussnitzer
- Shantanu Singh
- Beth A. Cimini
- Paul C. Blainey
- Anne E. Carpenter
- Calvin H. Jan
- James T. Neal
publisher: Cold Spring Harbor Laboratory
date: '2023-08-07'
link: https://doi.org/gszn2s
image: https://www.ncbi.nlm.nih.gov/corecgi/tileshop/tileshop.fcgi?p=PMC3&id=704470&s=171&r=2&c=2
tags:
- cell painting
- cell morphology
- assay
- id: 10.1101/2023.11.01.565179
title: Molecular subtypes of high-grade serous ovarian cancer across racial groups
and gene expression platforms
authors:
- Natalie R. Davidson
- Mollie E. Barnard
- Ariel A. Hippen
- Amy Campbell
- Courtney E. Johnson
- Gregory P. Way
- Brian K. Dalley
- Andrew Berchuck
- Lucas A. Salas
- Lauren C. Peres
- Jeffrey R. Marks
- Joellen M. Schildkraut
- Casey S. Greene
- Jennifer A. Doherty
publisher: openRxiv
date: '2023-11-04'
link: https://doi.org/gs3vwj
tags:
- ovarian cancer
- molecular subtypes
- racial disparities
- genomics
- id: doi:10.1016/j.xgen.2023.100340
title: 'OpenPBTA: The Open Pediatric Brain Tumor Atlas'
authors:
- Joshua A. Shapiro
- Krutika S. Gaonkar
- Stephanie J. Spielman
- Candace L. Savonen
- Chante J. Bethell
- Run Jin
- Komal S. Rathi
- Yuankun Zhu
- Laura E. Egolf
- Bailey K. Farrow
- Daniel P. Miller
- Yang Yang
- Tejaswi Koganti
- Nighat Noureen
- Mateusz P. Koptyra
- Nhat Duong
- Mariarita Santi
- Jung Kim
- Shannon Robins
- Phillip B. Storm
- Stephen C. Mack
- Jena V. Lilly
- Hongbo M. Xie
- Payal Jain
- Pichai Raman
- Brian R. Rood
- Rishi R. Lulla
- Javad Nazarian
- Adam A. Kraya
- Zalman Vaksman
- Allison P. Heath
- Cassie Kline
- Laura Scolaro
- Angela N. Viaene
- Xiaoyan Huang
- Gregory P. Way
- Steven M. Foltz
- Bo Zhang
- Anna R. Poetsch
- Sabine Mueller
- Brian M. Ennis
- Michael Prados
- Sharon J. Diskin
- Siyuan Zheng
- Yiran Guo
- Shrivats Kannan
- Angela J. Waanders
- Ashley S. Margol
- Meen Chul Kim
- Derek Hanson
- Nicholas Van Kuren
- Jessica Wong
- Rebecca S. Kaufman
- Noel Coleman
- Christopher Blackden
- Kristina A. Cole
- Jennifer L. Mason
- Peter J. Madsen
- Carl J. Koschmann
- Douglas R. Stewart
- Eric Wafula
- Miguel A. Brown
- Adam C. Resnick
- Casey S. Greene
- Jo Lynne Rokita
- Jaclyn N. Taroni
publisher: Cell Genomics
date: '2023-05-01'
link: https://doi.org/gr92p6
image: https://ars.els-cdn.com/content/image/1-s2.0-S2666979X23001155-fx1.jpg
repo: https://github.com/AlexsLemonade/OpenPBTA-analysis
tags:
- pediatric cancer
- brain tumor
- open science
- id: doi:10.1016/j.cels.2022.10.001
title: Morphology and gene expression profiling provide complementary information
for mapping cell state
authors:
- Gregory P. Way
- Ted Natoli
- Adeniyi Adeboye
- Lev Litichevskiy
- Andrew Yang
- Xiaodong Lu
- Juan C. Caicedo
- Beth A. Cimini
- Kyle Karhohs
- David J. Logan
- Mohammad H. Rohban
- Maria Kost-Alimova
- Kate Hartland
- Michael Bornholdt
- Srinivas Niranj Chandrasekaran
- Marzieh Haghighi
- Erin Weisbart
- Shantanu Singh
- Aravind Subramanian
- Anne E. Carpenter
publisher: Cell Systems
date: '2022-10-01'
link: https://doi.org/gq6hbw
image: https://www.cell.com/cms/attachment/55912f54-18d9-4ee9-8374-6f24f9d15bbc/fx1.jpg
repo: https://github.com/broadinstitute/lincs-profiling-complementarity
extra-links:
- type: data
link: broadinstitute/lincs-cell-painting
text: Reproducible data pipeline
- type: data
link: https://idr.github.io/idr0125-way-cellpainting/
text: Publicly-available Cell Painting images
- type: data
link: https://doi.org/10.6084/m9.figshare.13181966.v2
text: Publicly-available L1000 profiles
tags:
- cell painting
- drug discovery
- gene expression
- deep learning
- reproducibility
- id: doi:10.1371/journal.pcbi.1009888
title: Predicting drug polypharmacology from cell morphology readouts using variational
autoencoder latent space arithmetic
authors:
- Yuen Ler Chow
- Shantanu Singh
- Anne E. Carpenter
- Gregory P. Way
publisher: PLOS Computational Biology
date: '2022-02-25'
link: https://doi.org/gq6hbx
image: https://docs.google.com/drawings/d/e/2PACX-1vRzFGkZMf9ZfXb_q1rE1D9gAAczySfYZ4zyVl93l-zcRXv7sNtJpZTNp__9fmyaTl5MyccvtHh74i-I/pub?w=345&h=321
repo: broadinstitute/cell-painting-vae
extra-links:
- type: data
link: https://doi.org/10.5281/zenodo.5348067
text: Zenodo archive
tags:
- variational autoencoder
- cell painting
- drug discovery
- latent space arithmetic
- id: doi:10.1371/journal.pbio.3001419
title: A field guide to cultivating computational biology
authors:
- Gregory P Way
- Anne E Carpenter
- Casey S Greene
- Piero Carnici
- Benilton S Carvalho
- Michiel de Hoon
- Stacey Finley
- Sara JC Gosline
- Kim-Anh Le Cao
- Jerry SH Lee
- Luigi Marchionni
- Suzanne Sindi
- Fabian J Theis
- Jean YH Yang
- Elana J Fertig
publisher: PLOS Biology
date: '2021-10-07'
link: https://doi.org/gm3hdh
image: https://raw.githubusercontent.com/WayScience/waysciencelab.com/main/_posts/analysis/cultivating_compbio_map_us_centric.png
tags:
- open science
- essay
- call to action
- id: doi:10.1002/1873-3468.14067
title: 'Sharing biological data: why, when, and how'
authors:
- Samantha L. Wilson
- Gregory P. Way
- Wout Bittremieux
- "Jean\u2010Paul Armache"
- Melissa A. Haendel
- Michael M. Hoffman
publisher: FEBS Letters
date: '2021-04-11'
link: https://doi.org/gmmq7d
image: https://febs.onlinelibrary.wiley.com/cms/asset/4a3a1cde-1265-471c-87af-f7556d28db36/feb213824-toc-0001-m.jpg
tags:
- open science
- microscopy data
- id: doi:10.1091/mbc.E20-12-0784
title: Predicting cell health phenotypes using image-based morphology profiling
authors:
- Gregory P. Way
- Maria Kost-Alimova
- Tsukasa Shibue
- William F. Harrington
- Stanley Gill
- Federica Piccioni
- Tim Becker
- Hamdah Shafqat-Abbasi
- William C. Hahn
- Anne E. Carpenter
- Francisca Vazquez
- Shantanu Singh
publisher: Molecular Biology of the Cell
date: '2021-04-19'
link: https://doi.org/gmmq7f
image: https://www.molbiolcell.org/cms/10.1091/mbc.E20-12-0784/asset/images/medium/mbc-32-995-g001.gif
repo: broadinstitute/cell-health
extra-links:
- type: preprint
link: https://www.biorxiv.org/content/10.1101/2020.07.08.193938v2
- type: source
link: https://github.com/broadinstitute/cell-health
text: Analysis
tags:
- image-based profiling
- cell biology
- id: doi:10.1186/s13059-020-02021-3
title: Compressing gene expression data using multiple latent space dimensionalities
learns complementary biological representations
authors:
- Gregory P. Way
- Michael Zietz
- Vincent Rubinetti
- Daniel S. Himmelstein
- Casey S. Greene
publisher: Genome Biology
date: '2020-05-11'
link: https://doi.org/gg2mjh
image: https://raw.githubusercontent.com/greenelab/BioBombe/master/docs/favicon-192x192.png
repo: greenelab/biobombe
extra-links:
- type: preprint
link: https://doi.org/10.1101/573782
- type: source
link: https://github.com/greenelab/biobombe
text: Analysis
- type: data
link: https://greenelab.github.io/BioBombe/
text: Embeddings
tags:
- biological representations
- unsupervised learning
- cancer
- id: 10.1016/j.xgen.2023.100346
title: Discovering cellular programs of intrinsic and extrinsic drivers of metabolic
traits using LipocyteProfiler
authors:
- Samantha Laber
- Sophie Strobel
- Josep M. Mercader
- Hesam Dashti
- Felipe R.C. dos Santos
- Phil Kubitz
- Maya Jackson
- Alina Ainbinder
- Julius Honecker
- Saaket Agrawal
- Garrett Garborcauskas
- David R. Stirling
- Aaron Leong
- Katherine Figueroa
- Nasa Sinnott-Armstrong
- Maria Kost-Alimova
- Giacomo Deodato
- Alycen Harney
- Gregory P. Way
- Alham Saadat
- Sierra Harken
- Saskia Reibe-Pal
- Hannah Ebert
- Yixin Zhang
- Virtu Calabuig-Navarro
- Elizabeth McGonagle
- Adam Stefek
- "Jos\xE9e Dupuis"
- Beth A. Cimini
- Hans Hauner
- Miriam S. Udler
- Anne E. Carpenter
- Jose C. Florez
- Cecilia Lindgren
- Suzanne B.R. Jacobs
- Melina Claussnitzer
publisher: Cell Genomics
date: '2023-06-01'
link: https://doi.org/gsff72
image: https://www.biorxiv.org/content/biorxiv/early/2021/07/19/2021.07.17.452050/F1.large.jpg
tags:
- image-based profiling
- metabolism
- variant to function
- id: 10.1038/s41597-020-0458-y
title: Epigenomic profiling of neuroblastoma cell lines
authors:
- Kristen Upton
- Apexa Modi
- Khushbu Patel
- Nathan M. Kendsersky
- Karina L. Conkrite
- Robyn T. Sussman
- Gregory P. Way
- Rebecca N. Adams
- Gregory I. Sacks
- Paolo Fortina
- Sharon J. Diskin
- John M. Maris
- Jo Lynne Rokita
publisher: Scientific Data
date: '2020-04-14'
link: https://doi.org/gmndmm
image: https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fs41597-020-0458-y/MediaObjects/41597_2020_458_Fig1_HTML.png?as=webp
tags:
- gene regulation
- pediatric cancer
- id: 10.1186/s40478-019-0803-6
title: Immune landscapes associated with different glioblastoma molecular subtypes
authors:
- Maria Martinez-Lage
- Timothy M. Lynch
- Yingtao Bi
- Carolina Cocito
- Gregory P. Way
- Sharmistha Pal
- Josephine Haller
- Rachel E. Yan
- Amy Ziober
- Aivi Nguyen
- Manoj Kandpal
- "Donald M. O\u2019Rourke"
- Jeffrey P. Greenfield
- Casey S. Greene
- Ramana V. Davuluri
- Nadia Dahmane
publisher: Acta Neuropathologica Communications
date: '2019-11-29'
link: https://doi.org/gg7qrr
image: https://media.springernature.com/full/springer-static/image/art%3A10.1186%2Fs40478-019-0803-6/MediaObjects/40478_2019_803_Fig1_HTML.png?as=webp
repo: greenelab/gbm_immune_validation
extra-links:
- type: data
link: https://doi.org/10.5281/zenodo.195238
text: Zenodo archive
tags:
- gene expression deconvolution
- cancer
- glioblastoma
- id: 10.1182/bloodadvances.2019000303
title: Integrated phosphoproteomics and transcriptional classifiers reveal hidden
RAS signaling dynamics in multiple myeloma
authors:
- Yu-Hsiu T. Lin
- Gregory P. Way
- Benjamin G. Barwick
- Margarette C. Mariano
- Makeba Marcoulis
- Ian D. Ferguson
- Christoph Driessen
- Lawrence H. Boise
- Casey S. Greene
- Arun P. Wiita
publisher: Blood Advances
date: '2019-11-12'
link: https://doi.org/gg7m56
image: https://ash.silverchair-cdn.com/ash/content_public/journal/bloodadvances/3/21/10.1182_bloodadvances.2019000303/6/advancesadv2019000303absf1.png?Expires=1632888317&Signature=gyxBCxLAJuFoJyUnY-Re3Tx7FjQJW3eGp8O5R58Nf9ivPWiKomDxz198mYlFFrCs6t-gu0ROAi9Ka4pdaBM5iltSUr~Ert9N85mYKB3NdQ9VHUXLAb-~4igHfF~azabT~UGLx2g44C3qP3RGw1X45kCm-wcOkGLwppiFdBeO-kB-llMFDPHIUtWz4JijMZi3bkYcNe5e9zFW2aPQifNun-76wWa4cDmI4XUqi1VOFPATlMdNXbI5JNMkRwyAESfqA__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA
repo: greenelab/multiple-myeloma-classifier
extra-links:
- type: data
link: https://doi.org/10.5281/zenodo.2566059
text: Zenodo archive
tags:
- NF1
- RAS pathway
- cancer
- multiple myeloma
- id: 10.1016/j.celrep.2019.09.071
title: Genomic Profiling of Childhood Tumor Patient-Derived Xenograft Models to
Enable Rational Clinical Trial Design
authors:
- Jo Lynne Rokita
- Komal S. Rathi
- Maria F. Cardenas
- Kristen A. Upton
- Joy Jayaseelan
- Katherine L. Cross
- Jacob Pfeil
- Laura E. Egolf
- Gregory P. Way
- Alvin Farrel
- Nathan M. Kendsersky
- Khushbu Patel
- Krutika S. Gaonkar
- Apexa Modi
- Esther R. Berko
- Gonzalo Lopez
- Zalman Vaksman
- Chelsea Mayoh
- Jonas Nance
- Kristyn McCoy
- Michelle Haber
- Kathryn Evans
- Hannah McCalmont
- Katerina Bendak
- "Julia W. B\xF6hm"
- Glenn M. Marshall
- Vanessa Tyrrell
- Karthik Kalletla
- Frank K. Braun
- Lin Qi
- Yunchen Du
- Huiyuan Zhang
- Holly B. Lindsay
- Sibo Zhao
- Jack Shu
- Patricia Baxter
- Christopher Morton
- Dias Kurmashev
- Siyuan Zheng
- Yidong Chen
- Jay Bowen
- Anthony C. Bryan
- Kristen M. Leraas
- Sara E. Coppens
- HarshaVardhan Doddapaneni
- Zeineen Momin
- Wendong Zhang
- Gregory I. Sacks
- Lori S. Hart
- Kateryna Krytska
- Yael P. Mosse
- Gregory J. Gatto
- Yolanda Sanchez
- Casey S. Greene
- Sharon J. Diskin
- Olena Morozova Vaske
- David Haussler
- Julie M. Gastier-Foster
- E. Anders Kolb
- Richard Gorlick
- Xiao-Nan Li
- C. Patrick Reynolds
- Raushan T. Kurmasheva
- Peter J. Houghton
- Malcolm A. Smith
- Richard B. Lock
- Pichai Raman
- David A. Wheeler
- John M. Maris
publisher: Cell Reports
date: '2019-11-01'
link: https://doi.org/gg596n
image: https://ars.els-cdn.com/content/image/1-s2.0-S2211124719312689-gr1.jpg
repo: marislab/pdx-classification
extra-links:
- type: data
link: https://doi.org/10.5281/Zenodo.1475249
text: Zenodo archive
tags:
- pediatric cancer
- id: 10.1146/annurev-biodatasci-072018-021348
title: Discovering Pathway and Cell Type Signatures in Transcriptomic Compendia
with Machine Learning
authors:
- Gregory P. Way
- Casey S. Greene
publisher: Annual Review of Biomedical Data Science
date: '2019-07-20'
link: https://doi.org/ggns8p
image: https://d3i71xaburhd42.cloudfront.net/1faf6f4ced4693d61acbbdc592d349eb09dbe32c/19-Figure1.1-1.png
extra-links:
- type: preprint
link: https://doi.org/10.7287/peerj.preprints.27229v1
text: preprint
tags:
- review
- id: 10.1038/s41592-018-0230-9
title: Bayesian deep learning for single-cell analysis