diff --git a/core/src/components.d.ts b/core/src/components.d.ts
index b6521a11bd9..10900d3b0ee 100644
--- a/core/src/components.d.ts
+++ b/core/src/components.d.ts
@@ -3098,6 +3098,7 @@ export namespace Components {
           * The theme determines the visual appearance of the component.
          */
         "theme"?: "ios" | "md" | "ionic";
+        "updateRadiosTabindex": () => Promise<void>;
         /**
           * the value of the radio group.
          */
diff --git a/core/src/components/radio-group/radio-group.tsx b/core/src/components/radio-group/radio-group.tsx
index ab9ce1579cf..bab52d596ed 100644
--- a/core/src/components/radio-group/radio-group.tsx
+++ b/core/src/components/radio-group/radio-group.tsx
@@ -1,7 +1,7 @@
 import type { ComponentInterface, EventEmitter } from '@stencil/core';
 import { Build, Component, Element, Event, Host, Listen, Method, Prop, State, Watch, h } from '@stencil/core';
 import { checkInvalidState } from '@utils/forms';
-import { renderHiddenInput } from '@utils/helpers';
+import { debounce, renderHiddenInput } from '@utils/helpers';
 import { hostContext } from '@utils/theme';
 
 import { getIonTheme } from '../../global/ionic-global';
@@ -110,6 +110,15 @@ export class RadioGroup implements ComponentInterface {
     this.valueChanged(this.value);
   }
 
+  /** @internal - Recompute which radio has tabindex 0. Call when radios are added/removed. */
+  @Method()
+  async updateRadiosTabindex() {
+    this.scheduleTabindexUpdate();
+  }
+
+  /** Ensures that the tabindex update is debounced and only called once. */
+  private scheduleTabindexUpdate = debounce(() => this.setRadioTabindex(this.value), 0);
+
   private setRadioTabindex = (value: any | undefined) => {
     const radios = this.getRadios();
 
diff --git a/core/src/components/radio/radio.tsx b/core/src/components/radio/radio.tsx
index 5ca4bb8cf01..225ac4f7099 100644
--- a/core/src/components/radio/radio.tsx
+++ b/core/src/components/radio/radio.tsx
@@ -151,6 +151,7 @@ export class Radio implements ComponentInterface {
     if (radioGroup) {
       this.updateState();
       addEventListener(radioGroup, 'ionValueChange', this.updateState);
+      radioGroup.updateRadiosTabindex();
     }
   }
 
@@ -158,6 +159,7 @@ export class Radio implements ComponentInterface {
     const radioGroup = this.radioGroup;
     if (radioGroup) {
       removeEventListener(radioGroup, 'ionValueChange', this.updateState);
+      radioGroup.updateRadiosTabindex();
       this.radioGroup = null;
     }
   }