Likelihood calculation scales linearly with the data size, and with the model complexity, making optimization potentially slow. Furthermore, Langevin optimization can be integrated in a scheme for optimizing collective variables [@mouaffac2023], in which case a large number of model optimizations must be performed before collective variable optimization converges. When running folie in a shared-memory multiprocessor environment, likelihood computation is performed in a data-parallel way over the projected simulation trajectories.
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