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Description
** CL term**
plasmacytoid dendritic cell, CL:0000784
Rename plasmacytoid dendritic cell to plasmacytoid cell and delete exact synonyms 'DC2' and 'type 2 DC'
As described in PMID: 33481643 https://pubmed.ncbi.nlm.nih.gov/33481643/ ,
"recent studies that now suggest that mouse plasmacytoid DCs predominantly originate from a progenitor distinct from that which gives rise to most cDCs (23–25). Furthermore, the gene expression profile of plasmacytoid DCs is different from that of cDCs (26–28). Therefore, it appears that plasmacytoid DCs are divergent from cDCs, and we henceforth refer to these cells as plasmacytoid cells (PCs) rather than DCs."
"PC: plasmacytoid cell. PCs are capable of producing type I interferons upon infection. They mainly have a lymphoid
origin and are ontogenetically distinct from cDCs"
'DC2' and 'type 2 DC' are confused with 'cDC2', with is one of the two major subtypes of conventional dendritic cells