Chiron Platform

A foundation model platform for single-cell transcriptomics with privacy-preserving federated learning.

🎯 Overview

Chiron Platform is a cutting-edge solution for handling single-cell transcriptomics data at scale while preserving privacy through federated learning. The platform provides:

• 🔒 Privacy-First Architecture: Train models across multiple institutions without sharing raw data
• 📊 Tabular Data Modeling: Specialized handling of unordered single-cell data structure
• 🧬 Biological Context: Novel pretraining strategies capturing regulatory logic across diverse biological systems
• 🔄 Robust Integration: Support for cell type annotation, gene imputation, and multi-omics integration

🚀 Quick Start

Prerequisites

• Node.js (v16 or higher)
• pnpm (v8 or higher)

Installation

# Clone the repository
git clone https://github.com/your-org/chiron-platform.git
cd chiron-platform

# Install dependencies
pnpm install

# Start the development server
pnpm start

The application will be available at http://localhost:3000.

🛠️ Tech Stack

• Frontend

  • React 18 with TypeScript
  • TailwindCSS for styling
  • Zustand for state management
  • React Router for navigation

• Backend

  • Python-based microservices
  • Hypha RPC for client-server communication
  • Federated learning infrastructure

🏗️ Project Structure

chiron-platform/
├── src/                    # Source code
│   ├── components/         # React components
│   ├── store/             # State management
│   ├── utils/             # Utility functions
│   └── types/             # TypeScript type definitions
├── public/                 # Static assets
├── pages/                  # Page components
└── resources/             # Additional resources

🧪 Development

Available Scripts

• pnpm start: Start development server
• pnpm build: Build for production
• pnpm test: Run tests
• pnpm eject: Eject from create-react-app

Development Guidelines

• Follow TypeScript best practices and maintain type safety
• Use functional components with hooks
• Write tests for critical functionality
• Follow the established code style (enforced by ESLint and Prettier)

🤝 Contributing

We welcome contributions! Please see our Contributing Guidelines for details on how to submit pull requests, report issues, and contribute to the project.

📄 License

This project is licensed under the MIT License - see the LICENSE file for details.

🌟 Acknowledgments

• The single-cell genomics community
• Our institutional partners
• All contributors and maintainers

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Made with ❤️ by the Chiron Platform Team