IAV_tRIBOseq

Nano-tRNA-seq analysis

This repository contains the notebooks and figures for the Nano-tRNA-seq analysis associated with the manuscript:

Host tRNA modifications drive efficient translation of influenza A virus genome and impact host antiviral stress responses

Diana Roberta Ribeiro, Alexandre Nunes, Mie Monti, Laia Llovera, Maximilian Berg, Kira Kerkhof, Marisa Pereira, Ana Rita Guimarães, Stefanie Kaiser, Eva Maria Novoa, Daniela Ribeiro*, Ana Raquel Soares*

Repository contents

• analysis/ — auxiliary analysis files for notebooks (codon usage + percudani rules table)
• correlation/ — correlation plots and data between tRNA data and IAV codon usage
• counts/ — tRNA counts and metadata
• FINAL_FIGURES/ — figures generated for the study
• notebooks/ — analysis notebooks
• output_tables/ — tRNA differential expression analysis output tables
• ref/ — reference files used in the analysis

Notes

This repository is intended to accompany the manuscript and contains the material needed to inspect the Nano-tRNA-seq analysis outputs and figures.